Apr 28 2021 Read 6 Times
Researchers at the University of Birmingham working on extraction of the COVID-19 encounter complex in a form stable enough for identification of future drug target sites, have successfully used polymer-based molecular ‘cookie cutters’ to isolate the complex while keeping it embedded in the cell membrane, so preserving the full structure of the molecule in its original context.
The encounter complex is formed when the COVID-19 spike latches onto a binding site on an ACE-2 receptor, which is a complex protein embedded in cell membranes in the lungs and cells that line the nose and airways.
Although it was first isolated last year, the methods used involved full extraction of ACE-2 receptors from cell membranes; this removal of the membrane’s supportive structure affects the stability of the receptor, which makes it difficult to study its structure and function.
Apr 28, 2021
Chelsea Clinton s
KRISTEN BELL were very open with their kids about it.
Which wasn t too hard, because they ve always known about daddy s addiction issues. Maybe they know a little too much.
One time when their oldest daughter was three, Dax was getting ready to leave for an AA meeting. She asked him why he had to go, and he said, quote, Because I m an alcoholic and if I don t go there, then I ll drink and then I ll be a terrible dad.
She asked Dax if she could go too, and he said no, you have to be an alcoholic. So she said, quote, I m gonna be an alcoholic.
I appreciate Doug Call (His View, April 21) responding to one of my previous columns. I also appreciate the Daily News for allowing me to voice what Iâm convinced will be the vindicated position in the long run. Because the media megaphone is controlled by the architects of the lockdown poli… More Headlines